IndraLab

Statements


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sparser
"Since the binding of nsP3 and USP10 to G3BP inhibits SGs, we hypothesized that ICP8 binding might do the same."

sparser
"It was recently identified that a common canonical sequence motif, FGDF, mediates binding of the nsP3 and USP10 proteins to G3BP ."

sparser
"The model might also explain the elimination of binding of both nsP3 and USP10 to G3BP upon mutation of the glycine residue to alanine, which would restrict flexibility and thus hinder adequate positioning of the phenylalanine side-chains in the FGDF motifs."