IndraLab

Statements

USP15 deubiquitinates NFKBIA. 7 / 7
1 | 6
reach
"CSN associated USP15 can deubiquitinate IkappaBalpha after TNFalpha mediated stimulation of the NF-kappaB pathway XREF_BIBR."
28074857
reach
"In this report, it was postulated that a CSN associated deubiquitinylase (USP15) causes a deubiquitination of IkappaBalpha representing a negative feedback mechanism of IkappaBalpha degradation and NF-kappaB activation."
19656241
reach
"Schweitzer et al. reported that COP9 signalosome (CSN)-associated USP15 can deubiquitinate IkappaBalpha and regulates the activation of NF-kappaB XREF_BIBR."
26061460
reach
"Another report reveals that USP15 deubiquitinates IkappaBalpha and increases its re-accumulation, leading to reduced NF-kappaB activity [XREF_BIBR]."
28245560
ubibrowser
No evidence text available
reach
"The Cylindroma tumour suppressor protein (CYLD) de-ubiquitinates NEMO and TRAF2 [XREF_BIBR - XREF_BIBR], while USP15 reverses betaTRCP mediated ubiquitination of IkappaBalpha [XREF_BIBR]."
22212761
reach
"USP15 deubiquitinates IkappaBalpha and promotes its re-accumulation after TNF-alpha-induced degradation, leading to reduced NF-kappaB activity."
23727018