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"Our results support these findings, as depleting PRPF8 led to enhanced annexin V staining (Figure 2B) and enhanced cell death (Figure 2C) in uninfected cells."

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"In colorectal cancer, Abdel-Wahab et al. demonstrated that silencing PRPF8 in DLD1 colon cancer cells led to cell death, indicating that PRPF8 regulates both cell growth and apoptosis in colorectal cancer [51]."