IndraLab

Statements

TBK1 binds USP15. 6 / 6
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"To explore whether UBE2S acts together with USP15 to deubiquitinate the K63-linked ubiquitination of TBK1, we tested whether USP15 interacts with TBK1."
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"Interestingly, overexpressed SRA promoted the interaction between TBK1 and USP15 (Fig. 7C)."
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"As shown in Figure 7 A, USP15 did not directly interact with TBK1, and it only interacted with TBK1 in the presence of UBE2S. Consistent with these results, endogenous USP15 could only be immunoprecip[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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biogrid
No evidence text available
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biogrid
No evidence text available
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"In addition, USP15 interacts with TBK1 and inhibits its activity only in the presence of ubiquitin-conjugating enzyme UBE2C."
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