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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP4 activates DNA Breaks, Double-Stranded. 2 / 2

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"So far, however, we only have a relatively limited understanding of the DDR roles for deubiquitylation enzymes (DUBs), which mediate the processing of DNA end resection.In this study, we show that the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"These results suggest that USP4 promotes DSB repair by HR.HR is initiated by DNA end resection, which generates 3 ' ssDNA tails that are coated by RPA (Chen et al., 2013)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...