IndraLab

Statements

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"To identify expression trends that are associated with USP18 KD-driven differentiation, hierarchical clustering was performed on all significantly affected proteins (N = 117, Supplementary Table S4)."
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"Furthermore, we also show that ISG15 KD had no impact on differentiation nor did it prevent USP18 KD-mediated differentiation."
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"The results showed that Usp18 knockdown significantly increased the osteogenic potential of MSCs, whereas Usp21 deletion decreased the osteoblastic differentiation of MSCs (Fig. S1C–F)."
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"USP18 is necessary for Th17 differentiation and the development of CD11b dendritic cells [82,83]."
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