IndraLab

Statements


| 4

sparser
"KH1 and KH3 domains of PCBP2 can bind to a 7-nt DNA sequence (5’-AACCCTA-3’) and its RNA equivalent."

sparser
"Previous studies have showed that the domains KH1 and KH3 of PCBP2 interact with coxsackievirus RNA, which further affecting initiation of positive-strand RNA synthesis ( Ogram et al., 2010; Vogt and [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"The KH1 domain of PCBP2 binds near the cadicivirus GNRA tetraloop and is essential for initiation."

sparser
"In this model, the extensive interactions of PCBP2's KH1 domain with d10c would clearly be critical for its function and would account for the strict requirement for this domain in initiation on Type 1 IRESs ( xref , xref )."