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USP18 activates vemurafenib. 2 / 2

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"In vemurafenib-resistant BRAF V600E mutant melanoma cells, USP18 expression is significantly elevated, leading to higher cGAS protein levels."

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"These results suggest that USP18 can promote the resistance to vemurafenib in BRAF V600E mutant melanoma cells in nude mice by stabilizing cGAS expression.To investigate the effect of the USP18/cGAS a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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USP18 activates vemurafenib. 2 / 2

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