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OTUD1 activates apoptotic process. 3 / 4

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"Next, we confirmed that OTUD1 overexpression increased the cleavage of caspase-3 and PARP and subsequently increased apoptosis."

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"OTUD1 knockdown inhibited melatonin-induced Bim upregulation and apoptosis in cancer cells ."

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"Melatonin induces apoptotic cell death through Bim stabilization by Sp1-mediated OTUD1 upregulation."

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IndraLab

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OTUD1 activates apoptotic process. 3 / 4

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