IndraLab

Statements

USP7 deubiquitinates EZH2. 9 / 10
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"We report here that the PRC2 complex is physically associated with ubiquitin specific protease USP7 in cancer cells where USP7 acts to deubiquitinate and stabilize EZH2."
33849069
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"USP7 deubiquitinates and stabilizes EZH2 in prostate cancer cells."
32453339
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"USP7 could also deubiquitinate and stabilize EZH2 in prostate cancer cells [46]."
36878903
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"Recently, EZH2 was found to be a target substrate for USP7, and USP7 deubiquitinates and stabilizes EZH2 and promotes cell migration, invasion, and sphere-forming potential in prostate and colon cancer cells."
37762082
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"USP7 deubiquitinates and stabilizes EZH2 in prostate cancer cells."
32453339
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"In prostate cancer, USP7 mediates EZH2 deubiquitination and stabilizes EZH2 expression to increase metastatic invasive activity and enhance oncogenesis in mice [25] ."
37207700
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"USP7 can also deubiquitinate and stabilize EZH2 in prostate cancer cells [44]."
38254206
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"USP7 promoted the deubiquitination of EZH2, thereby accelerating prostate cancer cell metastasis [34]."
40329406
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"USP7 inhibition also induced EZH2 ubiquitination and degradation."
37762082