IndraLab

Statements


USP8 activates ERK. 2 / 2
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"USP8 activity thus modulates VEGF-A-stimulated Akt and ERK1/2 activation but does not affect other VEGFR2 associated signal transduction pathways."

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"Thus, the knockdown of USP8 significantly reduced the downstream targets of RTKs including STAT3, Akt, and ERKs both as a phosphorylated and unphosphorylated form in gefitinib-resistant and -sensitive[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"