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USP10 increases the amount of AICDA. 2 / 2

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"These results suggest that USP10 knockout in B cells decreases AID expression in B cells, thereby, decreasing IgG1 and IgA class-switch.AID is required for SHM and antibody affinity maturation."

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"c The fluorescence-field micrograph of identified AID-interacting deubiquitinase siRNA screen showed that USP10 knockdown dramatically decreased AID-GFP levels."

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IndraLab

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USP10 increases the amount of AICDA. 2 / 2

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