IndraLab

Statements


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"Hydroxychloroquine, which is used to treat some dermatologic and rheumatologic diseases because of its anti-inflammatory and immunosuppressive effects, is an uncommon cause of AGEP."

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"Luo et al. explored the clinical features and associated gene expression of AGEP induced in HCQ treated patients with rheumatic diseases including SLE, RA, or pSS, and showed that HCQ-induced AGEP might have a longer latency period and regression time than AGEP induced by other drugs."

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"The latent period of HCQ induced AGEP is longer than that of antibiotics induced AGEP, which are 12 ~ 30 days and 1 day, respectively XREF_BIBR."

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"[XREF_BIBR] We report a case of AGEP induced by hydroxychloroquine with systemic involvement."

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"Hydroxychloroquine (HCQ) is an uncommon cause of AGEP with a prolonged recovery course; Thus, the physicians should take the possibility of this rare but severe event in their minds and try to diagnose correctly and better management."

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"However, HCQ-induced AGEP is prolonged and recurrent, ranging from 7–81 d (18, 37)."

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"In some cases, hydroxychloroquine (HCQ) can cause AGEP."

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"Antibiotics, NSAIDs, opioids, anticonvulsants, hydroxychloroquine, and chemotherapy agents trigger AGEP."

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"3 In case of HCQ-induced AGEP, the latency period appears to be longer (ranging from 4 to 30 days 6 ) than in antibiotics-related cases, and the eruption tends to be more serious and resistant to treatments."

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"Several cases of AGEP induced by hydroxychloroquine have been reported in literature [24, 25]."