IndraLab

Statements

Epalrestat inhibits NLRP3. 3 / 3
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"Therefore, epalrestat may be useful and important for treating NLRP3-driven diseases.We also elucidated the mechanism by which epalrestat inhibits NLRP3 inflammasome in this study."
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"Epalrestat did not inhibit the NLRP3 inflammasome (XREF_FIG)."
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"The results showed that epalrestat, sulforaphane, parthenolide and OLT1177 could inhibit the activation of NLRP3 inflammasome at the concentration of 40 μmol/L, and epalrestat is more effective than OLT1177 at this concentration (Additional file 2)."
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