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"CsA substantially blocked activation of nuclear factor of activated T cells and cAMP responsive element binding protein (P < 0.001), inhibited CCAAT and enhancer binding protein by 50% (P < 0.05), and minimally blocked activator protein-1 and nuclear factor-kappaB responses to bacteria in epithelial cells."

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"Furthermore, CsA has been found to impede the activation of p38 and c-Jun N-terminal protein kinase."