IndraLab

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"Mechanistically, OTUD1 interacts with SEC23B, a component of the coat protein II complex (COPII)."

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"Our study thus explored the role of OTUD1 in moderating periodontitis by inhibiting neutrophil secretion, suggesting that the OTUD1SEC23B axis can be a potential target for the treatment of neutrophil‐related inflammatory diseases."

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"Interaction between OTUD1 and COPII subunits was confirmed by co‐immunoprecipitation assay, and OTUD1 associated strongly with SEC23B (Figure  xref )."