IndraLab

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USP5 inhibits STAT3. 2 / 2
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"Suppression deubiquitinase USP5 inhibits the inflammatory response of chronic periodontitis by suppressing STAT3 signaling."

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"In addition, the downregulation of USP5 and its related deubiquitinating enzyme activity inhibited the lipopolysaccharide (LPS)-induced inflammatory response of human periodontal ligament stem cells and also prevented the activation of the STAT3 signaling pathway [64]."