IndraLab

Statements


U0126 inhibits NFKBIA. 2 / 2
| 2

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"Although the oleate activated AKT, IkappaBalpha and ERK were inhibited by LY294002, parthenolide and U0126, respectively, only LY294002 and parthenolide significantly inhibited the oleate induced PTX3 expression."

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"U0126 inhibition of IkappaBalpha processing is specific for the TPA signal transduction pathway, since this inhibitor did not interfere with TNF-alpha-induced processing of IkappaBalpha (lanes 10-12)."