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Mutated USP1 leads to the deubiquitination of SNAI1. 1 / 1
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"Accordingly, compared to USP1 , expression of USP1 mutant did not lead to Snail de-ubiquitination (Fig. 4F), and from a biological point of view, it failed to protect OVCAR-8 cells from CDDP-induced cell death (Fig. 4G)."