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OTUD3 binds KPTN. 4 / 4
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"Our experiments indicated that the OTU domain plays a pivotal role in the interaction between OTUD3 and KPTN (Figures 1D, E)."
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No evidence text available
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"Through this method, we found that there is a potential interaction between the deubiquitinating enzyme OTUD3 and KPTN, which is one of the components of the KICSTOR protein complex, an important regulatory factor in the mTORC1 signaling pathway.Researchers have identified gene mutations in the breast cancer cell lines involving OTUD3, leading to loss of protein function and accelerating the migration and metastasis of cancer cells."
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"Thus, these results validated the interaction between OTUD3 and KPTN."
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