IndraLab

Statements


USP20 inhibits OGD/R. 2 / 2
| 2

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"UCMSCs-derived exosomal SLIT2 activated TCF4 by promoting β-catenin nuclear translocation, which transcriptionally upregulated USP20 expression, thereby attenuating OGD/R-induced neuroncell damage and ultimately leading to inhibition of IS progression."

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"Intriguingly, USP20-inhibited inflammation and neuron damage were considerably abrogated by PTEN suppression in OGD/R-incubated cells."