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Doxycycline increases the amount of UCHL1. 2 / 2
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"As shown in Figure XREF_FIG A, cell death in untreated UCH-L1 tet-on podocytes was negligible whereas induction of UCH-L1 expression by doxycycline significantly increased the numbers of dying podocytes (thereby also demonstrating the functionality of the system)."
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"Differentiated podocytes exhibited a concentration ( Fig. 4 A) and time-dependent ( Fig. 4 B) over-expression of UCH-L1 in response to doxycycline."
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