IndraLab

Statements


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reach
"Pyk2 recruitment to SHPS-1 is mediated via the interaction of Pyk2 Tyr402 and the Src in response to IGF-I."

sparser
"Recruitment of FYB/SLAP-130 to SHPS-1 required SKAP55hom/R, whereas PYK2 associated with SHPS-1 independently."

reach
"Skaphom, ADAP and Pyk2 associate constitutively with Shps1, but become tyrosyl phosphorylated upon adhesion [34]."

reach
"Recruitment of FYB and SLAP -130 to SHPS-1 required SKAP55hom/R, whereas PYK2 associated with SHPS-1 independently."

reach
"Thus, Pyk2 recruitment to SHPS-1 plays an important role in regulating the IGF-I-stimulated mitogenic response."

reach
"Recruitment of Pyk2 to SHPS-1 signaling complex is required for IGF-I-dependent mitogenic signaling in vascular smooth muscle cells."

sparser
"We reconstituted the interaction of SHPS-1 with either PYK2 or SKAP55hom/R ()."