IndraLab

Statements

OTUB2 activates RIPK2. 2 / 2

| 2

reach

"Mechanistically, OTUB2 inhibited the proteasomal degradation of RIPK2 by removing K48-linked polyubiquitination on RIPK2, which was mediated by the active C51 residue in OTUB2."

39358938

➶

reach

"Upon MDP stimulation, OTUB2 promoted NOD2 signaling by stabilizing RIPK2."

39358938

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

OTUB2 activates RIPK2. 2 / 2

INDRA sources:

Databases

Reading