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"Additionally, USP38 and USP28 both interact with DNA damage response proteins (GO response to ionizing radiation, FDR =7.0 × 10 and 3.0 × 10 for USP38 and USP28 respectively), supporting the hypothesis that these DUBs are involved in DNA repair (Figure 3b)."

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"The alterations in DNA damage (Fig. 5C) and inhibition of DNA repair (Fig. 5D) induced by USP28 silencing were also consistent with AZ1 treatment."