IndraLab

Statements


BAP1 inhibits ATP. 4 / 4
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"Moreover, BAP1 fibroblasts enhance aerobic glycolysis and lactate secretion, but reduce mitochondrial respiration and ATP production, when compared with wild-type BAP1."

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"BAP1 inhibits glucose deprivation induced reactive oxygen species and ATP depletion, two cellular events contributing to the ER stress induced cell death."

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"BAP1 +/- fibroblasts displayed increased aerobic glycolysis and lactate secretion, and reduced mitochondrial respiration and ATP production compared with BAP1 WT."

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"Intact BAP1 catalytic activity could increase aerobic glycolysis and lactate secretion and reduce mitochondrial respiration and ATP production [49]."