IndraLab

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OTUD6B inhibits cell population proliferation. 3 / 3

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"In normal and transformed cells, the expression of the OTUD6B isoform that represses protein synthesis and proliferation is quantitatively higher."

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"Further, lncRNA OTUD6B can inhibit ccRCC cell proliferation by suppressing the Wnt and beta-catenin pathway and the expressions of epithelial-to-mesenchymal transition related proteins."

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"The ability of OTUD6B to inhibit tumor proliferation was further verified in vivo in a nude mouse model ( Figure 10F )."

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INDRA sources:

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IndraLab

Statements

OTUD6B inhibits cell population proliferation. 3 / 3

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