IndraLab

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USP36 activates cell growth. 3 / 3
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"In CCK8 and colony formation assays, elevated RBM28 enhanced cell proliferation and reversed the cell growth decreased by USP36 knockdown."
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"Through CCK8 and colony formation assays, we found that Idasanutlin (a p53 activator) markedly suppressed cell proliferation and counteracted the increased cell growth driven by the overexpression of USP36 and RBM28 in LoVo cells (Fig. S7A, B)."
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"Conversely, RBM28 depletion attenuated cell proliferation and restored the enhanced cell growth caused by USP36 overexpression (Fig. S5A–D)."
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