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USP46 deubiquitinates NRAS. 1 / 1
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"Together, these results indicate that USP46 specifically deubiquitinates and stabilizes NRAS Q61R/K mutants in melanoma but not NRAS WT, KRAS WT, HRAS WT and their mutants.We next examined the specific ubiquitin linkage of NRAS mutants cleaved by USP46."