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USP4 increases the amount of CDH2. 2 / 2

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"In line with previous studies, we also showed that USP4 promoted melanoma metastasis by suppressing E-cadherin expression and increasing N-cadherin expression, indicating the ubiquitous existence of the crosstalk between USP4 and EMT in different kinds of cancer."

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"Moreover, we performed RT-PCR experiment, and it also showed that the knockdown of USP4 could significantly decrease N-cadherin and increase E-cadherin expression at the transcriptional level."

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IndraLab

Statements

USP4 increases the amount of CDH2. 2 / 2

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