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USP1 binds WDR48 and WDR20. 1 / 1

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"In addition, the USP1-Uaf-1-WDR20 complex directly deubiquitinates and stabilizes the Akt phosphatases PHLPP and PHLPPL, leading to a decrease in active pAkt levels, which then downregulates AR phosphorylation and enhances AR stability and transcriptional activity."

37752518

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IndraLab

Statements

USP1 binds WDR48 and WDR20. 1 / 1

INDRA sources:

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