IndraLab

Statements

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"With regard to the top novel epilepsy-associated predictions, CACNA1B is associated with the voltage-gated calcium channel that has been only recently implicated in epileptic phenotypes. xref , xref , xref USF1 deficiency in mice (in combination with USF2 knockout) has been shown to cause epileptic seizures, xref suggesting the important role this gene plays in normal brain function."
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"Co-immunoprecipitations from brain tissue is consistent with the formation of a protein complex between RB-3α and RB-3β and both Cav2.2 and the related Cav2.1 calcium channel."
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