IndraLab

Statements


USP2 increases the amount of UCP2. 2 / 2
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reach
"Considering that the tissue distribution of USP2 is also relatively ubiquitous [50], USP2 might prevent oxidative stress in various tissues through the preservation of UCP2.The lack of USP2 dramatically repressed UCP2 at the mRNA level, implying that USP2 stimulates the transcription of the Ucp2 gene."

reach
"Since we did not demonstrate the involvement of PGC1α in USP2-modulated UCP2 expression, we cannot exclude the possibility that USP2 promotes Ucp2 expression via other transcriptional regulators."