IndraLab

Statements


6 | 2 1

reach
"A Duolink in situ proximity ligation assay (PLA) kit (DUO92101, Sigma-Aldrich) was used to detect the interaction between PAH and USP19 and to evaluate the ubiquitination status of PAH."

sparser
"Our study indicates that USP19 interacts with PAH and prevents polyubiquitination of PAH subsequently extending the half-life of PAH protein."

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reach
"As shown in Fig. 3b, in situ USP19 and PAH interaction was observed in the form of PLA dots when USP19 and PAHwt or the PAH variants were immunostained together (Fig. 3b, left panel), but not when they were stained with either USP19 or PAH antibody alone (Fig. 3b, right panel)."

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