IndraLab

Statements


OTUB2 activates CC. 5 / 5
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"Knockdown of OTUB2 suppressed CC cell growth whereas OTUB2 upregulation fostered the proliferation of cancer cells."

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"FOXM1 was found to play a critical role in OTUB2-mediated CC cell growth."

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"OTUB2 promotes CC progression through deubiquitinating and stabilizing FOXM1."

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"Inhibition of OTUB2 promotes apoptosis and attenuates proliferation and metastasis of CC cells by downregulating the AKT/mTOR signalling pathway (Ref."

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"As indicated by CCK-8, Transwell, and flow cytometry results, OTUB2 silencing attenuated proliferative and metastatic capacities of CC cells but promoted CC cell apoptosis."