IndraLab

Statements

NEDD4L ubiquitinates KCNQ1. 4 / 4
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"Therefore, it is possible that α 1 AR activates AMPK to lead to KCNQ1 internalization via ubiquitination of KCNQ1 by Nedd4-2."
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"enDUBs selectively reverse NEDD4L ubiquitination of KCNQ1."
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"enDUBs selectively reverse NEDD4L ubiquitination of KCNQ1."
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"Nedd4-2 can also ubiquitinate the KCNQ1 potassium channel, resulting in KCNQ1 's removal from the cell surface, internalization and degradation by the proteasome [XREF_BIBR], a reaction that can be counteracted by the de-ubiquitinylating enzyme USP2 [XREF_BIBR]."
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