IndraLab

Statements

Luteolin inhibits CASP1. 6 / 6
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"In parallel, luteolin inhibited caspase-1 activation and IL-1β processing in J774A.1 and BMDM by interfering with ASC-complex formation, even in the event without affecting pro-IL-1β, pro-caspase-1 (p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Luteolin could also suppress the production and release of HMGB1 and the activation of caspase 1 both in LPS-induced mice and LPS/ATP-stimulated HepG2 cells."
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"Luteolin inhibits tumor growth by inducing pyroptosis via caspase-1/GSDMD signaling (19)."
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"The results clearly demonstrate that the naturally derived compounds, quadrangularin and luteolin potentially inhibit ROCK2 and Caspase-1 with high binding affinity, and showed stable conformation throughout simulation trajectory period."
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"Luteolin supplementation at 50 or 100 µM for 24 h reduced NLRP3 and caspase-1 at mRNA and protein levels in glucose-treated podocyte [19] ."
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"Yu et al. reported that AIM2, pro-caspase-1, caspase-1 p10, pro-IL-1β, and IL-1β were inhibited by luteolin in vitro and in vivo [84]."
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