IndraLab

Statements


OTUD5 activates STING1. 3 / 3
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"On the other hand, OTUD5 and USP20 catalyze the K48-linked deubiquitination of STING and inhibit STING degradation, thus maintain the stability of STING and promote activation of STING pathway (87–89)."

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"Similarly, OTUD5 promotes the protein stability of STING via cleaving the K48-linked polyubiquitin chains."

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"On the other hand, OTUD5 and USP20 catalyze the K48-linked deubiquitination of STING and inhibit STING degradation, thus maintain the stability of STING and promote activation of STING pathway (87) (88) (89) ."