IndraLab

Statements


MYC increases the amount of USP10. 4 / 4
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"USP10 transcription induced by c-Myc improved the stability of the p14ARF protein [69] ."

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"C-Myc directly binds to the second E-box sequence of the USP10 gene and activates the transcription of USP10 [69]."

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"USP10 also antagonizes c-myc transcription through deubiquitination of SIRT6, a histone deacetylase, and NF-kappaB signaling through deubiquitination of NEMO [XREF_BIBR]."

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"MYC activates USP10 transcription by binding to the second E-box sequence located upstream of the USP10 transcription start site."