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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Ct-HBx inhibits USP16. 3 / 3

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"[ 94-96 ] Transcriptional downregulation of ubiquitin specific peptidase 16 ( USP16 ) by Ct-HBx is also shown to enhance tumorigenicity and stem-like properties of HCC cells ."

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"The aforementioned results revealed the tumour-suppressive functions of USP16, which could be downregulated by Ct-HBx in liver tumour cells."

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"In conclusion, our study suggests that USP16 is negatively regulated by Ct-HBx and plays a critical role in the pro tumorigenicity of Ct-HBx proteins."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...