IndraLab

Statements

EGF leads to the phosphorylation of USP8 on tyrosine. 3 / 3
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"Moreover, EGF stimulation of EGFR induces USP8 tyrosine phosphorylation while, in contrast, TGF-alpha reduces tyrosine phosphorylation [131]."
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"These results show that EGF stimulation of EGFR-ERBB4 CYT-1 triggers USP8 tyrosine phosphorylation and demonstrate that USP8 is part of the ERBB4 signaling cascade."
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"This model is supported by our current findings that TGFalpha stimulation of EGFR and EGF stimulation of ERBB2 [52], conditions that are associated with enhanced endosomal recycling and decreased MVB [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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