IndraLab

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USP9X activates BCL2. 1 / 1
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"Peddaboina et al. also found that USP9X inhibition downregulated MCL1, an anti-apoptotic factor in the BCL2 (BCL2, apoptosis regulator) gene family, thereby increasing the sensitivity of solid tumor cells to various chemotherapeutic agents, including Bcl-2/Bcl-XL inhibitors."