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Statements

Apigenin inhibits RELA. 7 / 10
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"Apigenin could decrease MyD88, p-IκB-α, and NF-κB p65 which indicates its protective effects against inflammation and atherosclerotic plaque formation."
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"In murine bone marrow derived DCs Apigenin was shown to reduce cell-surface expression of antigen presentation and co-stimulatory molecules in a NF-κB (p65)-dependent manner (Yoon et al. 2006)."
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"Our studies performed through EMSA demonstrate that chamomile inhibits RelA and p65 activation."
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"Our studies performed through EMSA demonstrate that chamomile inhibits RelA and p65 activation."
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"As shown in Fig. 4 , we found that Apigenin and Luteolin significantly inhibited NF-κB activation induced by overexpression of NF-κB p65 and GAL4DBD-p65/RelA, indicating that these flavonoids inhibit [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"They found that apigenin activated the Nrf2 pathway and suppressed the transcriptional activation of nuclear p65, which may partly contribute to the hepatoprotective effects (Zhao et al., 2020)."
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"Mehmet et al. demonstrated that Apigenin can inhibit the signaling cascades of NF-κB p65 and MAPKs, reduce oxidative stress and neutrophil infiltration, and increase enzymatic and nonenzymatic antioxidant levels in liver cells, thus treating LPS-induced liver injury [29]."
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