IndraLab

Statements

TNF inhibits TNFAIP3. 6 / 6
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"By contrast, the addition of exogenous TNF-α restored the reduced levels of TNFAIP3 mRNA observed in the HDAC3-deprived cells at 240 min after the LPS challenge.These results suggested that inflammatory TNFAIP3 mRNA induction was indirectly blocked by TSA via the suppression of endogenous TNF-α at later time points, while direct HDAC inhibition may have been responsible for the earlier time point blockade."
36077149
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"Similarly, significantly increased expression level of miR-19b-3p (Ashraf et al., 2016), miR-29b (Thounaojam et al., 2014a), and miR-301a (Hazra et al., 2019) stimulate microglia secrete inflammatory mediators in JEV-infected BV2 cells, including TNF-α, IL-6, and IL-1β, via separately decreasing RNF11, TNFAIP3 and NKRF, which are all negative regulators of NF-κB signaling pathway."
35479613
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"Figure 5 shows that, in scr cells, the neutralization of endogenous TNF-α significantly decreased TNFAIP3 mRNA accumulation only at 240 min."
36077149
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"In order to gain insight in the relative contribution of SLPI as an inhibitor of NF‐κB, we measured mRNA expression of the other known NF‐κB inhibitors TNF‐α‐induced protein 3 (TNFAIP3), single Ig and TIR domain containing (SIGIRR) and Toll‐interacting protein (TOLLIP) in THP‐1 cells."
36480463
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"Homozygous deletions of the chromosomal band 6q23, involving the tumor necrosis factor alpha induced protein 3 (TNFAIP3, A20) gene, a negative regulator of NF-kappa B, had already been described in ocular adnexal MZL."
20309425
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"TNF stimulation of Rela +/- splenocytes resulted in significantly impaired up-regulation of Il6, Tnfaip3, and Traf1; all which depend on NF-kappaB activation (XREF_FIG)."
28600438