IndraLab

Statements

ADCY9 binds KCNQ1. 3 / 4
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"More importantly, it can form a complex with AC9 and KCNQ1 to regulate slow outward potassium ion current in cardiac cells, underscoring its crucial role in sympathetic regulation of the heart[ 26-29 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"We now show that either AC2 or AC9 can associate with KCNQ1 in a complex mediated by Yotiao."
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"It is thought that AC9 binds to KCNQ1 channels via A-kinase anchor protein and promotes the repolarization phase of the action potential during sympathetic nerve stimulation, thereby increasing heart rate [ xref ]."
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