IndraLab

Statements


TP53 bound to TP53, TP53, and TP53 activates TP53. 1 / 1
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"<p17> Ser392 phosphorylation of P53 increases 10-fold the association constant for tetramerization, but this effect is reversed by Ser315 phosphorylation. The tetramerization activates P53 for specific DNA binding and transcription"