IndraLab

Statements

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"There may be a variety of mechanisms involved in OTUB1 promoting the metastasis of colorectal cancer."
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"OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer."
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"These data suggest that OTUB1‐isoform2 promotes ovarian tumour growth and metastasis in vivo.4 DISCUSSION."
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"In this sense, OTUB1 may promote colon cancer proliferation, metastasis and recurrence through TGFbeta signal pathway."
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"OTUB1 promotes CRC metastasis by facilitating EMT and acts as a potential distant metastasis marker and prognostic factor in CRC."
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"Recently, OTUB1 was demonstrated to promote the metastasis of esophageal cancer by stabilizing Snail."
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"OTUB1 promotes esophageal squamous cell carcinoma metastasis through modulating Snail stability."
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"These results revealed that OTUB1 promoted CRC cell liver metastasis in vivo."
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"OTUB1 also promoted the metastasis of CRC cell lines in vitro and in vivo by regulating EMT."
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"OTUB1 contributes to drug resistance and promotes metastasis."
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"Indeed, OTUB1 has been reported to promote metastasis by facilitating EMT [XREF_BIBR]."
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"Together, our findings demonstrate that OTUB1 promotes the migration, invasion, and metastasis of CRC cells in vitro and in vivo and acts as a potential metastasis marker and prognostic factor in CRC."
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"Successful inhibition of OTUB1 enzymatic activity is expected to downregulate TAZ and eventually prevents metastasis of aggressive cancers, such as BL-TNBC."
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