IndraLab

Statements

KCNH1 binds CNBHD. 4 / 4
| 4
reach
"The crystal structure of eag and CNBHD complex of mEAG channel has suggested that the coupling between eag and CNBHD is involved in EAG channel gating regulated by eag domain [XREF_BIBR]."
28367272
reach
"The model of CNBHD and eag complex of the hERG channel can be obtained based on the X-ray structure of the complex of the mouse EAG channel XREF_BIBR (XREF_FIG)."
27025590
reach
"The crystal structure of eag and CNBHD complex provides a promising approach for generating specific drugs targeting eag and CNBHD complex, the most distinct part of EAG1 channel compared to other Kv channels."
28367272
reach
"However, pursuing for a specific EAG1 channel gating inhibitor by targeting the eag and CNBHD complex failed to find any high affinity leads [XREF_BIBR]."
28367272