IndraLab

Statements


PRKN inhibits ATXN3. 3 / 4
| 3

reach
"SNP rs1801582 in PRKN lowers the AAO of MJD patients."

reach
"Similarly, overexpression of the E3 ubiquitin ligase parkin induces ataxin-3 degradation and reduces aggregation and toxicity."

reach
"Overexpression of parkin reduces aggregation and cytotoxicity of an expanded polyglutamine ataxin-3 fragment."