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UCHL1 deubiquitinates SMAD2. 2 / 2
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ubibrowser
"We also found that UCH-L1 interacts, deubiquitinates, and stabilizes SMAD2 and SMAD3."
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reach
"In a separate study using a DUB activity profiling approach Liu et al. identified UCHL1 as a particularly active DUB in TNBC, proposing that UCHL1 also promotes TGF-β-induced TNBC metastasises by deubiquitinating and stabilising TGFβR1 and SMAD2 [54]."
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